A Deeper Shade of Green—Sustainable Trends in Pharmaceutical Laboratory and Cleanroom Retrofits

Gary Shamshoian, LEED® AP, Genentech
Michael Trzepacz, X-nth

The challenge of retrofit projects in pharmaceutical laboratory and cleanrooms will be presented with an emphasis on sustainable technologies. Case studies in various retrofit projects will focus on the sustainable features that improved the facilities life cycle value while controlling capital costs. The importance of bold planning, integrated building design, and implementing ahead-of-the-curve solutions will be discussed. The challenges of retrofits in critical, validated facilities and introducing engineering innovations with a focus on sustainable lifecycle value improvements will be addressed from an owner and design team viewpoint. Lessons learned and industry trends will be detailed as appropriate technologies are implemented to improve the value of our engineering efforts.

Identifying value added improvements from a component, system, facility, and enterprise level is critical to progress in the application of innovative engineering solutions. Sustainability improvements of mechanical systems are realized through improvements in first costs, resource consumption, maintenance, reliability, operations, and qualification strategies. The dynamics of the introduction of ideas and risk sharing between the owner and design team will be presented. Driving ongoing improvements in the effective use of capital through sharing lessons learned and knowledge management will be presented.

Examples and current case studies will be presented to emphasize these aspects of sustainable engineering.

Biographies:

Gary Shamshoian, P.E., LEED AP, is a mechanical engineer at Genentech Roche, South San Francisco, California, where his focus is on sustainable mechanical design, installation, and qualification activities. His first exposure to high-performance building design was in 2001 when the Lawrence Berkeley National Laboratory (LBNL) A Team provided design assistance to fit a filling facility on a top floor planned to support laboratories. Permit issues restricted penthouse expansion, so the team minimized equipment sizing through energy efficiency by reducing pressure drops and using HVAC recirculation fans. When the team realized they still needed a small penthouse expansion, they knew that they saved significant capital costs through HVAC capacity reductions in addition to the energy savings. Applying integrated design strategies has provided three ENERGY STAR® office buildings and more than three negawatts of savings from laboratory and cleanroom efficiency improvements. Maintenance and reliability improvements generated major savings on many projects and standardization and knowledge management have encouraged innovation.

Past experiences from other pharmaceutical and high technology owner representative, mechanical, electrical, and plumbing (MEP) coordinator for general contractors, and design roles have shown the importance of HVAC design and indoor air quality challenges. Learning from contractors and application oriented partners helps to foresee installation, maintenance, and reliability issues before project impacts.

Mr. Shamshoian received a Masters of Science in mechanical engineering from the University of Colorado, Boulder, and holds a Bachelor of Science in mechanical engineering from Stanford University.

Michael Trzepacz is a registered professional engineer with more than 22 years of project management, engineering, and design experience. As a principal for X-nth San Francisco, Mr. Trzepacz is responsible for project management, contract administration, master planning, scheduling, engineering, design, specification, and commissioning for science and technology facilities, including biotechnology, pharmaceuticals, forensic sciences, vivariums, academic medical research, and healthcare facilities. As a leader at X-nth, Mr. Trzepacz works directly with owners, architects, and construction managers to help accelerate project schedules and add project flexibility with detailed attention to technical accuracy and maintaining project budgets. Mr. Trzepacz has many years of experience delivering projects in the California Bay Area and providing engineering design with the constructability perspective of a builder and the maintainability perspective of a facility manager.